Senior Associate, HEOR 8

Over six years of experience in the HEOR/RWE space with proven expertise in RWE studies using SAS based on claims, EMR, and registry data. Rich background in categorical data analysis, survival analysis, randomized trial designs analysis, macro definitions, debugging programs, and documentation in both SAS and R programming environments. Expert in Advanced Excel/VBA including mastery […]

<strong>Erenumab Study Demonstrates Significantly Reduced Acute Medication Usage<br>and Health Care Utilization for Migraines</strong>

A recent study of the fully human monoclonal antibody erenumab was designed to evaluate real-world evidence on the impact of erenumab on acute medication usage and health care utilization (HCRU) among migraine patients. The Health Economics and Outcomes Research analyst team, tasked by Novartis and managed by Lujia Zhou, KMK Consulting, Inc., conducted a retrospective […]

Migraine Study Demonstrates Impact of Treatment Failures on Healthcare System

Summary: The economic burden caused by treatment failures of migraine was explored in a study led by Dr. Lujia Zhou, KMK Consulting, Inc. The study results, published in The Journal of Neurology, “Economic Burden Increased with Number of Treatment Failures in Migraine Patients -A Retrospective Claims Database Analysis in the United States (1485),”demonstrated clearly that […]

It is time to use an Interactive Flow Diagram to Tell Patient Narratives

With the ever-increasing degree of digitalization of health records of various kinds, it has never been easier to track different facets of a patient’s journey. Not only it is now possible to trace all the different events associated with one particular medical encounter, there are also ways and means to probe into what happens before […]

How to become the Iron Man of Data Analytics?

Do you feel sluggish or lethargic most days? Are you susceptible to catching colds? If you blame the “daily grind” for why you’re feeling rundown, you might be overlooking a simple nutrient deficiency. Iron is needed to make hemoglobin — part of our red blood cells that carries oxygen to the body’s tissues. In addition, […]

Exploring the significance of Real World Evidence and Real World Data

The terms Real World Evidence (RWE) and Real World Data (RWD) appear more and more in industry discussions and within FDA reports. The pharma industry is embracing RWE and it is quickly becoming the next big thing in industry intelligence. FDA guidelines have been published for using RWE in clinical studies and the FDA is […]

Smarter Real World Evidence: A Flexible Client-Centered Dashboard Can Help Data Tell a Better Story

If analyzed correctly, compelling data can serve business needs and reveal commercial opportunities. The KMK Real World Evidence Dashboard is a customized client-centered approach to help biopharmaceutical companies reach intuitive conclusions faster, save significant time on re-analysis, and improve recall and comprehension with a clean graphical approach to sharing the story inherent in the data. […]

HEOR Principal Huanxue Zhou’s Manuscript in International Journal of MS Care

KMK HEOR Principal Huanxue Zhou‘s latest manuscript, Impact of Switching to Fingolimod Versus Injectable Disease-Modifying Therapy Cycling on Risk of Multiple Sclerosis-Related Relapses, was published in the International Journal of MS Care. A PDF of the article is available for download. BACKGROUND Clinical and real-world studies have shown significant reductions in MS relapses in patients receiving fingolimod versus […]

Real World Evidence to Support Payer Negotiation

How do you prove a product’s value to negotiate pricing with a payer?  Our client, a large global pharmaceutical company, was facing a market access problem for their newly launched product. Generic treatments have been widely available for many years in this particular therapeutic category. Although the efficacy of our client’s product has been demonstrated […]